22 Mar 2024

IASC - Routinely collected data in clinical trials: methods, opportunities and challenges

Date 22 Mar 2024
Time 14:00 GMT+01:00 - 15:30 GMT+01:00
Level of instruction Intermediate
Dorcas Kareithi
Registration fee

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SLIDES Dorcas Kareithi

Clinical trials are studies that evaluate interventions their effects on human health outcomes. These interventions could be focused on prevention, diagnosis or treatment. Trials typically involve the careful selection and random assignment of participants into treatment and control groups, allowing researchers to assess the intervention's impact while minimizing bias. A typical clinical trial setting involves observation of the outcomes, and analysis of the difference in outcomes. However, one may need to evaluate the effectiveness or safety of interventions in routine clinical practice (external validity), investigate long-term outcomes beyond the trial period or encounter clinical trials with recruitment challenges. In this webinar, we will have a look at some of the statistical considerations of routinely collected data can be used in clinical trials, show one example of how this was used, what more can be done and what are some of the challenges.


Dorcas Kareithi
Dorcas Kareithi

About the instructor

Dorcas Kareithi is an associate statistician (clinical trials and health research) with the Biostatistics Research Group at Newcastle University, UK. Previously, she was the Head of Research at Co-Creation Hub Limited, sitting at the Design Lab in Kigali, Rwanda. Dorcas holds a MSc. in Biometry/Biostatistcs from the University of Nairobi and a BSc. in Economics and Mathematics, Kabarak University. Dorcas has over a decade of experience in the health industry as an analyst, researcher and epidemiological consultant and working with several organisations in Africa and abroad to develop, implement and evaluate health products and services. Dorcas is passionate about empowering young people, more so young and upcoming statisticians in Africa, to ensure that the statistician’s workforce in Africa grows. She does this through mentoring other statisticians and organising, coordinating and supporting activities aimed at equipping statisticians with technical and soft skills, including statistical literacy. Dorcas is the current president of Young African Statisticians Association (YASA), a country coordinator (Kenya) of the International Statistical Literacy Program (ILSP), an active member of the International Statistical Institute/International Association for Statistical Computing (ISI/IASC), and Organisation for Women in Science for the Developing World (OWSD).